6-hydroxypicolinic acid - Names and Identifiers
Name | 6-hydroxypicolinic acid
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Synonyms | 6-hydroxypicolinic acid 6-CARBOXY-2-HYDROXY-PYRIDINE 6-HPA, 6-hydroxypicolinic acid 2-Hydroxy-6-PyridineCarboxylicAcid 6-Hydroxy-2-PyridineCarboxylicAcid 2-CARBOXY-1,6-DIHYDRO-6-OXOPYRIDINE 6-Hydroxypyridine-2-carboxylic acid 6-oxo-1,6-dihydropyridine-2-carboxylate 6-oxo-1,6-dihydropyridine-2-carboxylic acid 6-oxo-1,6-dihydropyridine-3-carboxylic acid 2-PYRIDINECARBOXYLIC ACID, 1,6-DIHYDRO-6-OXO 6-Hydroxypicolinic acid, 6-Hydroxypyridine-2-carboxylic acid 6-Hydroxypyridine-2-carboxylic acid,6-Hydroxypicolinic acid, 6-Hydroxypyridine-2-carboxylic acid
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CAS | 19621-92-2
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EINECS | 417-690-8 |
InChI | InChI=1/C6H5NO3/c8-5-3-1-2-4(7-5)6(9)10/h1-3H,(H,7,8)(H,9,10)/p-1 |
InChIKey | VRCWSYYXUCKEED-UHFFFAOYSA-N |
6-hydroxypicolinic acid - Physico-chemical Properties
Molecular Formula | C6H5NO3
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Molar Mass | 139.11 |
Density | 1.451±0.06 g/cm3(Predicted) |
Melting Point | 270 °C (dec.) (lit.) |
Boling Point | 436.0±45.0 °C(Predicted) |
Flash Point | 217.5°C |
Vapor Presure | 8.03E-09mmHg at 25°C |
Appearance | Yellow powder |
Color | Yellow to brown |
BRN | 115842 |
pKa | 3.29±0.20(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
MDL | MFCD00192220 |
Physical and Chemical Properties | Light yellow powder |
6-hydroxypicolinic acid - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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WGK Germany | 3 |
HS Code | 29333990 |
Hazard Class | IRRITANT |
6-hydroxypicolinic acid - Introduction
6-hydroxyacrylic acid (6-hydroxyacrylic acid), also known as 6-Pyridin-2-olcarboxylic acid, is an organic compound.
Nature:
-Appearance: 6-hydroxyypicolinic acid is a colorless or slightly yellow crystal or crystalline powder.
-Solubility: Soluble in water, alcohols and Ether solvents.
-Chemical properties: It is a weak acid that can react with alkali to form the corresponding salt.
Use:
-Chemical reagent: 6-hydroxyypicolinic acid is often used as a ligand of coordination compounds and can be used to synthesize metal complexes.
-Drug intermediate: It can be used to synthesize drugs containing pyridine ring structure.
Method:
The preparation of 6-hydroxypicolinic acid can be carried out by the following methods:
1. Pyridine and methanol react in the presence of oxygen to obtain 6-hydroxy-2-picolinic acid. Then the esterification reaction was carried out under alkaline conditions to obtain 6-hydroxyypicolinic acid.
Safety Information:
-6-hydroxyicolinic acid may be irritating to the eyes, skin and respiratory system, please avoid direct contact.
-When using, do a good job in laboratory safety operations, wear appropriate personal protective equipment, such as laboratory gloves and goggles.
-storage should be sealed, avoid contact with oxygen, acid and alkali.
-In case of inhalation or misuse, please seek medical attention.
Last Update:2024-04-09 02:00:44